Targeting steroid therapy in rheumatoid arthritis.
نویسندگان
چکیده
منابع مشابه
Intra-articular steroid therapy in rheumatoid arthritis.
The introduction of steroid preparations into joint cavities has become a routine method of treating some cases of rheumatoid arthritis. Murdoch and Will (1959a, b) have drawn attention to the persistence of prednisolone trimethyl acetate (P.T.M.A.) in the joint cavity and to its, apparently, purely local effect when administered in this way. Since then, Triamcinolone (T.C.A.), Dexamethasone (D...
متن کاملStatin therapy for targeting cardiovascular risk in rheumatoid arthritis
For many years, rheumatoid arthritis (RA), a prototypical immune-mediated inflammatory disease, has been attributed to increased cardiovascular morbidity and mortality, irrespective of established risk factors [1–4]. In the early 1990s, it was demonstrated that RA may shorten overall survival with mortality rates being in the range of twofold or more. It was observed that increased mortality is...
متن کاملTargeting Angiogenesis in Rheumatoid Arthritis.
Angiogenesis, the development of new capillaries, is a crucial process in health and disease. The perpetuation of neovascularization in rheumatoid arthritis is highly involved in leukocyte extravasation into the synovium and pannus formation. Numerous soluble and cell surface-bound angiogenic mediators, including growth factors, cytokines, proteases, matrix macromolecules, cell adhesion recepto...
متن کاملSex steroid receptors in rheumatoid arthritis.
Rheumatoid arthritis (RA) is a disease characterized primarily by chronic inflammatory synovitis and is well-known to be associated with significant sex differences in its prevalence and clinical features. Sex steroids have been proposed to be involved in the pathogenesis of RA, but details pertaining to the expression of sex steroid receptors in RA synovial tissue have yet to be fully characte...
متن کاملComparing bone mineral density in rheumatoid arthritis and psoriatic arthritis
Background: Changes in patients’ bone mineral density (BMD) is one of the problems in patients with rheumatoid arthritis, which can be due to the use of corticosteroid drugs to reduce patients' symptoms or due to the aging process in patients. In this study, we decided to compare BMD in patients with psoriatic arthritis and rheumatoid arthritis. Methods: This study as a cross-sectional descrip...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1983
ISSN: 0003-4967
DOI: 10.1136/ard.42.4.479